GeneTex Antibodies

Manufacturer: GeneTex Antibodies

The COL1A1 antibody [N1N2], N-terminal, is a polyclonal antibody derived from rabbits and provided unconjugated. This antibody targets the N-terminal region of human COL1A1 (Collagen Type I Alpha 1 Chain), a critical extracellular matrix protein involved in maintaining structural integrity in connective tissues.

Manufacturer: GeneTex Antibodies

The Claudin 3 antibody [HL1527], available from GeneTex and other suppliers like Novus Biologicals, is a rabbit monoclonal antibody designed for research applications. It is specific to the intracellular domain of human Claudin-3, a component of tight junctions critical for cellular barrier functions.

Manufacturer: GeneTex Antibodies

This monoclonal antibody specifically detects phosphorylated Chk1 at serine 345 (Ser345), a key phosphorylation site involved in the DNA damage response and cell cycle regulation. Chk1 (Checkpoint kinase 1) is a critical kinase in the cellular response to DNA damage, and its activation through phosphorylation at Ser345 plays a crucial role in cell cycle arrest and DNA repair. This antibody is highly valuable for studying DNA damage checkpoint signaling, cancer research, and drug development targeting the DNA repair machinery.

Manufacturer: GeneTex Antibodies

The CD97 antibody [HL1925] specifically targets CD97, a seven-transmembrane G protein-coupled receptor (GPCR) that plays a significant role in cell signaling, adhesion, and migration. CD97 is involved in various physiological and pathological processes, including immune cell activation, tissue remodeling, and cancer metastasis. This antibody is ideal for studies on inflammation, immune response, and cancer research. The [HL1925] clone is highly specific to human CD97, making it a valuable tool for cellular and molecular research.

Manufacturer: GeneTex Antibodies

This monoclonal antibody specifically targets CD90, also known as Thy-1, a glycosylphosphatidylinositol (GPI)-anchored cell surface protein involved in cell adhesion, differentiation, and signaling. CD90 is predominantly expressed on stem cells, hematopoietic cells, and a variety of cancer cells, making it an essential marker for stem cell research, cancer immunology, and regenerative medicine. The [HL1766] clone has high specificity for human CD90 and is suitable for a wide range of applications in cell biology and immunology.

Manufacturer: GeneTex Antibodies

This monoclonal antibody targets CD44, a cell surface glycoprotein involved in cell-cell interactions, cell adhesion, and migration. CD44 is expressed in various cell types, including hematopoietic cells, stem cells, and tumor cells, making it a crucial marker in cancer research, stem cell biology, and immunology. CD44 is also involved in inflammatory responses, wound healing, and tissue regeneration. The [HL1650] clone specifically recognizes a high-affinity isoform of CD44.

Manufacturer: GeneTex Antibodies

This high-quality antibody specifically recognizes Caspase 3, a critical cysteine-aspartic acid protease involved in the execution phase of apoptosis. Caspase 3 activation is a hallmark of programmed cell death and is widely studied in cancer, neurodegenerative diseases, and cell signaling pathways. This antibody is ideal for detecting both the proenzyme and cleaved active forms of Caspase 3.

Manufacturer: GeneTex Antibodies

This monoclonal antibody is designed to recognize the complement component 3 (C3) and its activated fragment, C3b, specifically targeting the C-terminal region. C3 plays a pivotal role in the complement cascade, contributing to innate immune defense. Dysregulation of C3 is associated with various immune disorders, making this antibody a valuable tool for immunology research.

Manufacturer: GeneTex Antibodies

This monoclonal antibody specifically targets B-Raf, a serine/threonine-protein kinase involved in the MAPK/ERK signaling pathway, which regulates cell division, differentiation, and secretion. Mutations in the B-Raf gene, such as V600E, are commonly associated with various cancers, making it a critical target for cancer research and therapeutic development.