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Manufacturer: Abbkine Scientific

SPRR genes encode a novel class of polypeptides called small proline-rich proteins that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. Small proline-rich protein 2A is a protein encoded by the SPRR2A gene.Gibbs et al. (1993) concluded that there are 7 genes for the SPRR2 subfamily of small proline-rich proteins, including SPRR2A.Using DNA microarray analysis, Zimmermann et al. (2005) identified Sprr2a and Sprr2b (182268) as allergen-induced genes in a mouse model of experimental asthma. By analysis of human-rodent hybrid cell lines and FISH, Gibbs et al. (1993) determined that all SPRR genes, including SPRR2A, are closely linked within a 300-kb DNA segment on chromosome 1q21-q22.

Manufacturer: Abbkine Scientific

Minami et al. (1987) reported the full-length cDNA and complete primary structure of human LTA4 hydrolase. This was the first report of the molecular cloning of an enzyme involved in the biosynthesis of eicosanoids. Funk et al. (1987) isolated a cDNA clone corresponding to leukotriene A4 hydrolase from a human lung lambda-gt11 expression library by immunoscreening with a polyclonal antiserum.

Manufacturer: Abbkine Scientific

Acetylcholine (Ach) is produced by the synthetic enzyme choline acetyltransferase which uses acetyl coenzyme A and choline as substrates for the formation of acetylcholine.Dietary choline and phosphatidylcholine serve as the sources of free choline for acetylcholine synthesis. Upon release, acetylcholine is metabolized into choline and acetate by acetylcholinesterase, and other nonspecific esterases. Acetylcholine release can be excitatory or inhibitory depending on the type of tissue and the nature of the receptor with which it interacts.

Manufacturer: Abbkine Scientific

Receptor-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the RIPK1 gene. RIPK1 is known to have function in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis)

Manufacturer: Abbkine Scientific

TIGIT encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. The predicted 244-amino acid TIGIT protein has a single Ig domain, followed by a type I transmembrane domain and a single intracellular immunoreceptor tyrosine-based inhibitory motif. It shares 88%, 67%, and 58% amino acid identity with its rhesus, dog, and mouse homologs, respectively.

Manufacturer: Arbor Assays

The 11-Ketotestosterone ELISA Kit quantitatively measures 11-Ketotestosterone in urine, extracted plasma, extracted serum, and dried fecal extracts. This competitive ELISA has a run time of 2.5 hours. Please read the complete kit insert for more information before performing this assay. Use our provided 11-Ketotestosterone standard to generate a standard curve for the assay.

Manufacturer: Arbor Assays

The 17-Hydroxyprogesterone ELISA Kit quantitatively measures 17-Hydroxyprogesterone (17HO-P) in extracted serum, extracted plasma, urine, fecal extracts, and tissue culture media. This competitive ELISA has a run time of 1.5 hours. Please read the complete kit insert for more information before performing this assay. Use our provided 17HO-P standard to generate a standard curve for the assay.

Manufacturer: Arbor Assays

The DetectX® 2′,3′-Cyclic GAMP ELISA Kit quantitatively measures 2’,3’-cGAMP present in lysed cells and tissue, EDTA plasma, and tissue culture media samples. This competitive ELISA has a run time of 2.5 hours. Please read the complete kit insert before performing this assay. Use our provided 2’,3’-Cyclic GAMP (cGAMP) standard to generate a standard curve for the assay.

Manufacturer: Cusabio

The mouse cTnI ELISA Kit quantitates mouse cTnI levels in serum and plasma. cTnI (TNNI3) is uniquely expressed in cardiac sarcomeres. It is the inhibitory component of the heterotrimeric troponin complex (cTn) that controls calcium ion-dependent activation of sarcomeres. cTnI functions as a key modulatory protein in cardiac muscle contraction and relaxation, combining calcium ion-troponin C (TnC) binding with activation of cross-bridge reactions with the thin filament. Increased serum levels of cTnI are identified as highly sensitive and specific indicators of myocardial injury. Serial determination of cTnI is routinely applied in the evaluation of patients with the acute coronary syndrome (ACS) for diagnosis and prognosis.