Search Result

Manufacturer: Affinity Biosciences Antibody

The Silent Information Regulator (SIR2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. The first discovered and best characterized of these genes is Saccharomyces cerevisiae SIR2, which is involved in silencing of mating type loci, telomere maintenance, DNA damage response, and cell aging . SirT1, the mammalian ortholog of Sir2, is a nuclear protein implicated in the regulation of many cellular processes, including apoptosis, cellular senescence, endocrine signaling, glucose homeostasis, aging, and longevity

Manufacturer: Elabscience

This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

Manufacturer: Elabscience

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Manufacturer: Elabscience

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Manufacturer: Abbkine Scientific

Rat Adiponectin (ADP) ELISA Kit employs a two-site sandwich ELISA to quantitate Adiponectin in samples.

Manufacturer: Abbkine Scientific

Rat Super Oxidase Dismutase (SOD) ELISA Kit employs a two-site sandwich ELISA to quantitate SOD in samples.

Manufacturer: Abbkine Scientific

Rat Estradiol (E2) ELISA Kit employs a two-site sandwich ELISA to quantitate E2 in samples.

Manufacturer: Elabscience

HS Rat IL-1β(Interleukin 1 Beta) ELISA Kit applies to the in vitro quantitative determination of Rat IL-1β concentrations in serum, plasma and other biological fluids.

Manufacturer: Elabscience

HS Rat IL-10(Interleukin 10) ELISA Kit applies to the in vitro quantitative determination of Rat IL-10 concentrations in serum, plasma and other biological fluids.