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Manufacturer: GeneTex Antibodies

The Zika virus NS4B protein antibody [HL1663] (Cat. No. GTX637261), a recombinant rabbit monoclonal antibody designed for the detection of the NS4B protein in Zika virus (ZIKV) studies.

Manufacturer: GeneTex Antibodies

The ZO-1 antibody [HL1133] (Cat. No. GTX636399), a recombinant rabbit monoclonal antibody designed for the detection of ZO-1, a key protein in tight junctions.

Manufacturer: GeneTex Antibodies

COX4, also known as cytochrome c oxidase subunit IV isoform 1, is a nuclear-encoded component of cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain. This enzyme complex facilitates electron transfer from cytochrome c to molecular oxygen, contributing to the proton gradient essential for ATP synthesis. Antibodies targeting COX4 are valuable tools for detecting this protein in various research applications, including Western blotting, immunohistochemistry, and immunofluorescence.

Manufacturer: GeneTex Antibodies

The HLA-B7 antibody [BB7.1] is a mouse monoclonal antibody that specifically targets the human HLA-B7 antigen, a class I major histocompatibility complex (MHC) molecule involved in presenting endogenous peptides to cytotoxic T cells. This antibody is widely utilized in immunological research, particularly in flow cytometry (FACS) applications, to detect HLA-B7 expression on the surface of human cells.

Manufacturer: GeneTex Antibodies

The NFκB p105 antibody [HL1784] is a recombinant rabbit monoclonal antibody that specifically targets the NFκB p105 protein, a precursor of the p50 subunit integral to the NFκB transcription factor complex. NFκB plays a pivotal role in regulating immune responses, inflammation, and cell proliferation.

Manufacturer: GeneTex Antibodies

The SOX2 antibody [HL1193] is a recombinant rabbit monoclonal antibody that specifically targets the SOX2 protein, a pivotal transcription factor essential for maintaining stem cell pluripotency and regulating embryonic development. SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors, playing a crucial role in the regulation of embryonic development and the determination of cell fate.

Manufacturer: Elabscience

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Manufacturer: Elabscience

CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

Manufacturer: Elabscience

CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.