Manufacturer: Elabscience
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Manufacturer: Elabscience
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Manufacturer: GeneTex Antibodies
The ACE2 antibody [HL1092] is a rabbit monoclonal antibody developed for laboratory research applications. This antibody targets the angiotensin-converting enzyme 2 (ACE2) protein, which is involved in the regulation of cardiovascular and renal functions and serves as a receptor for the SARS-CoV-2 spike protein.
Manufacturer: GeneTex Antibodies
The AKT antibody [N3C2], Internal (GTX121937), offered by GeneTex, is designed for the detection of AKT protein across multiple applications including Western blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), and Immunoprecipitation (IP).
Manufacturer: GeneTex Antibodies
The alpha Smooth Muscle Actin antibody [HL1419] from GeneTex is a monoclonal antibody commonly used in research to identify alpha-smooth muscle actin, a protein involved in cellular contractility, structure, and tissue integrity. It is particularly useful for studies involving vascular smooth muscle, fibroblast-to-myofibroblast differentiation, and fibrotic diseases.
Manufacturer: GeneTex Antibodies
The ASFV p54 antibody [HL1218] is a recombinant monoclonal antibody designed to detect the African Swine Fever Virus (ASFV) p54 protein. This protein is a key component of the ASFV envelope, crucial for virus attachment to host cells and entry into the cytoplasm. The antibody is available in an unconjugated, carrier-free format and is suitable for various applications, including Western Blot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), and ELISA
Manufacturer: GeneTex Antibodies
The ATM (phospho Ser1981) antibody [HL1062] is a recombinant rabbit monoclonal antibody that specifically detects the phosphorylated form of ATM at Ser1981. ATM, or Ataxia Telangiectasia Mutated, is a serine/threonine kinase involved in the cellular response to DNA damage, particularly double-strand breaks. It plays a critical role in cell cycle regulation, DNA repair, and apoptosis, particularly following exposure to ionizing radiation. The antibody is particularly useful for research involving DNA damage repair, cell cycle checkpoints, and apoptosis.
Manufacturer: GeneTex Antibodies
The ATR (phospho Thr1989) antibody [HL132] is a rabbit monoclonal antibody that specifically detects the phosphorylated form of ATR (Ataxia Telangiectasia and Rad3-Related) protein at the threonine 1989 site. ATR plays a critical role in the cellular response to DNA damage and is crucial for checkpoint activation during DNA replication stress.
Manufacturer: GeneTex Antibodies
The Bax antibody [HL236] is a recombinant monoclonal antibody designed to detect Bax, a pro-apoptotic protein involved in regulating cell death. This antibody is suitable for use in techniques like Western blot (WB) and immunohistochemistry (IHC-P), with proven reactivity in human, mouse, and rat species. The immunogen for this antibody is a synthetic peptide derived from the N-terminus region of human Bax.