Jonlnbio Elisa Kit

Manufacturer: Jonlnbio

Syntenin-2 is a protein that is encoded by the SDCBP2 gene.The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Manufacturer: Jonlnbio

Syndecan-3 is a protein that is encoded by the SDC3 gene.The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.

Manufacturer: Jonlnbio

Serpin B3 is a protein that is encoded by the SERPINB3 gene.Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.SERPINB3 is a Protein Coding gene. Diseases associated with SERPINB3 include Lung Non-Small Cell Carcinoma and Squamous Cell Carcinoma. Among its related pathways are Innate Immune System and Pancreatic cancer subtypes.

Manufacturer: Jonlnbio

Transforming protein RhoA, also known as Ras homolog family member A (RhoA), is a small GTPase protein in the Rho family of GTPases that in humans is encoded by the RHOA gene.[5] While the effects of RhoA activity are not all well known, it is primarily associated with cytoskeleton regulation, mostly actin stress fibers formation and actomyosin contractility. It acts upon several effectors. Among them, ROCK1 (Rho-associated, coiled-coil containing protein kinase 1) and DIAPH1 (Diaphanous Homologue 1, a.k.a. hDia1, homologue to mDia1 in mouse, diaphanous in Drosophila) are the best described.

Manufacturer: Jonlnbio

Ras-related C3 botulinum toxin substrate 1, is a protein thatis encoded by the RAC1 gene. This gene can produce a variety of alternatively spliced versions of the Rac1 protein, which appear to carry out different functions.Rac1 is a small (~21 kDa) signalling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of GLUT4 translocation to glucose uptake, cell growth, cytoskeletal reorganization, antimicrobial cytotoxicity, and the activation of protein kinases.

Manufacturer: Jonlnbio

Olfactomedin 4 is a protein that is encoded by the OLFM4 gene.Thisgenewasoriginally cloned from human myeloblasts and found to be selectivelyexpressedininflamed colonic epithelium. This gene encodes a member of the olfactomedinfamily. The encoded protein is an antiapoptotic factor that promotes tumorgrowthand is an extracellular matrix glycoprotein that facilitates cell adhesion.

Manufacturer: Jonlnbio

Mucin-5AC (MUC-5AC) is a protein that is encoded by the MUC5AC gene.MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract, it protects against infection by binding to inhaled pathogens, which are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease, and has also been associated with greater protection against influenza infection.

Manufacturer: Jonlnbio

Mucin-17 is a protein that is encoded by the MUC17 gene.Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.

Manufacturer: Jonlnbio

Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da) proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic, lead) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues.There are four main isoforms expressed (family 1, see chart below): MT1 (subtypes A, B, E, F, G, H, L, M, X), MT2, MT3, and MT4.