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Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Human Matrix Metalloproteinase 1 (also known as MMP1) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Human Galectin-3 (also known as LGALS3) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Porcine Interleukin 2 (also known as IL2) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Human Adropin (also known as AD) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Human Adropin (also known as AD) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This Sandwich kit is for the accurate quantitative detection of Human Intelectin-1 (also known as ITLN1) in serum, plasma, cell culture supernatants, Ascites, tissue homogenates or other biological fluids.

Manufacturer: BT Lab

This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Human GDNF antibody. GDNF present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Human GDNF Antibody is added and binds to GDNF in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated GDNF antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Human GDNF

Manufacturer: BT Lab

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Manufacturer: BT Lab

Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity). In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).