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Manufacturer: Abbkine Scientific

EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, parotid gland. It can also be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.

Manufacturer: Prospec Bio

Il-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of b-cells into ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.

Manufacturer: Prospec Bio

IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa. IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Manufacturer: Abbkine Scientific

Rat Adiponectin (ADP) ELISA Kit employs a two-site sandwich ELISA to quantitate Adiponectin in samples.

Manufacturer: Abbkine Scientific

Rat Super Oxidase Dismutase (SOD) ELISA Kit employs a two-site sandwich ELISA to quantitate SOD in samples.

Manufacturer: Abbkine Scientific

Rat Estradiol (E2) ELISA Kit employs a two-site sandwich ELISA to quantitate E2 in samples.

Manufacturer: Elabscience

HS Rat IL-1β(Interleukin 1 Beta) ELISA Kit applies to the in vitro quantitative determination of Rat IL-1β concentrations in serum, plasma and other biological fluids.

Manufacturer: Elabscience

HS Rat IL-10(Interleukin 10) ELISA Kit applies to the in vitro quantitative determination of Rat IL-10 concentrations in serum, plasma and other biological fluids.

Manufacturer: Elabscience

HS Human IL-6(Interleukin 6) ELISA Kit applies to the in vitro quantitative determination of Human IL-6 concentrations in serum, plasma and other biological fluids.