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Manufacturer: Jonlnbio

Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells.The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines.CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

Manufacturer: Jonlnbio

Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene (GRO3), GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b). CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2.

Manufacturer: Jonlnbio

Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.The Nobel Prize in Physiology or Medicine 2019 was awarded for the discovery of HIF.HIF1A is a basic helix-loop-helix PAS domain containing protein, and is considered as the master transcriptional regulator of cellular and developmental response to hypoxia.

Manufacturer: Jonlnbio

Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Manufacturer: Jonlnbio

Lactoferrin (LF), also known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of PMNs and is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly.Lactoferrin is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses.It is constantly produced and released into saliva, tears, as well as seminal and vaginal fluid.

Manufacturer: Jonlnbio

Oxytocin (OT) is a polypeptide hormone and neuropeptide normally produced by the hypothalamus and released by the posterior pituitary gland. It plays a role in social relationships, reproduction, labor and delivery and during the postpartum period. It acts as a hormone that is released into the bloodstream during sexual activity and childbirth. In either form, oxytocin stimulates uterine contractions and speeds up the labor process. The production and secretion of oxytocin is controlled by a positive feedback mechanism in which its initial release stimulates the production and release of further oxytocin. For example, when oxytocin is released during uterine contractions at the beginning of labor, this stimulates the production and release of more oxytocin and increases the intensity and frequency of contractions. This process increases in intensity and frequency and continues until the triggering activity ceases.

Manufacturer: Jonlnbio

Luteinizing hormone (LH) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus.LH is a heterodimeric glycoprotein, each monomer unit is a glycoprotein molecule, which is a functional protein composed of an α subunit and a β subunit. Its structure is similar to that of other glycoprotein hormones, follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH) and human chorionic gonadotropin (hCG).

Manufacturer: Jonlnbio

Luteinizing hormone (LH) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. LH is a heterodimeric glycoprotein, a functional protein consisting of one subunit and one subunit. Its structure is similar to that of other glycoprotein hormones, follicle-stimulating hormone (FSH), thyrotropin (TSH) and human chorionic gonadotropin (hCG).The protein dimer contains 2 glycopeptidic subunits (labeled alpha- and beta- subunits) that are non-covalently associated.

Manufacturer: Jonlnbio

Luteinizing hormone (LH) is a hormone produced by gonadotropic cells in the anterior pituitary gland. The production of LH is regulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus.LH is a heterodimeric glycoprotein, each monomer unit is a glycoprotein molecule, which is a functional protein composed of an α subunit and a β subunit. Its structure is similar to that of other glycoprotein hormones, follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH) and human chorionic gonadotropin (hCG).