Manufacturer: Jonlnbio
This kit recognizes Mouse NAG in samples. No significant cross-reactivity or interference between Mouse NAG and analogues was observed.
Manufacturer: Jonlnbio
Galectin-4 is a protein that is encoded by the LGALS4 gene.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer. The 323-amino acid LGALS4 protein contains two homologous, approximately 150-amino acid carbohydrate recognition domains and all amino acids typically conserved in galectins.
Manufacturer: Jonlnbio
Galectin-7 is a protein that is encoded by the LGALS7 gene.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the suprabasal layers where it concentrated to areas of cell-to-cell contact.
Manufacturer: Jonlnbio
Granulysin (GNLY) is a protein expressed in most mammals which functions as an antimicrobial peptide released by killer lymphocytes in cytotoxic granules.It is a pore-forming peptide, as it can puncture a microbial cell wall, allowing for other death-inducing enzymes to enter the microbe and cause microptosis.GNLY is inhibited by cholesterol, and is most effective in helping to kill cholesterol-deficient microbes.
Manufacturer: Jonlnbio
Milk fat globule-EGF factor 8 protein (Mfge8), also known as lactadherin, is a protein that is encoded by the MFGE8 gene.MFGE8 may function as a cell adhesion protein to connect smooth muscle to elastic fibers in arteries. An amyloid fragment of MFGE8 known as medin accumulates in the aorta with aging.[8] MFGE8 in the vasculature of adults can induce recovery from ischemia by facilitating angiogenesis. It has been suggested that antagonizing MFGE8-induced angiogenesis could be a way of fighting cancer.
Manufacturer: Jonlnbio
Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da) proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic, lead) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues.There are four main isoforms expressed (family 1, see chart below): MT1 (subtypes A, B, E, F, G, H, L, M, X), MT2, MT3, and MT4.
Manufacturer: Jonlnbio
Mucin-17 is a protein that is encoded by the MUC17 gene.Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.
Manufacturer: Jonlnbio
Mucin-5AC (MUC-5AC) is a protein that is encoded by the MUC5AC gene.MUC-5AC is a large gel-forming glycoprotein. In the respiratory tract, it protects against infection by binding to inhaled pathogens, which are subsequently removed by mucociliary clearance. Overproduction of MUC-5AC can contribute to diseases such as asthma and chronic obstructive pulmonary disease, and has also been associated with greater protection against influenza infection.
Manufacturer: Jonlnbio
Olfactomedin 4 is a protein that is encoded by the OLFM4 gene.Thisgenewasoriginally cloned from human myeloblasts and found to be selectivelyexpressedininflamed colonic epithelium. This gene encodes a member of the olfactomedinfamily. The encoded protein is an antiapoptotic factor that promotes tumorgrowthand is an extracellular matrix glycoprotein that facilitates cell adhesion.