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Manufacturer: Elabscience

Biotinidase, also known as biotinase and BTD, is a ubiquitous mammalian cell enzyme which expressed at high levels in the liver, serum, and kidney. Its primary function is to cleave biotin from biocytin, preserving the pool of biotin for use as a cofactor for biotin dependent enzymes, namely the 4 human carboxylases. Biotinidase also recycles biotin from enzymes in the body that use it as a helper component in order to function. These enzymes, known ascarboxylases, are important in the processing offats,carbohydrates, andproteins. Biotin is attached to these carboxylase enzymes through anamino acid(the building material of proteins) calledlysine, forming a complex calledbiocytin.

Manufacturer: Elabscience

Alpha-amylase is the major form of amylase found in humans and other mammals. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. Alpha-amylase hydrolyses alpha bonds of large, alpha-linked polysaccharides, such as starch and glycogen, yielding glucose and maltose. Amylases is widely expressed and is most prominent in pancreatic juice and saliva, each of which has its own isoform of human α-amylase. They behave differently on isoelectric focusing, and can also be separated in testing by using specific monoclonal antibodies.

Manufacturer: Elabscience

PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family; PPIL3 subfamily. PPIase contains 1 PPIase cyclophilin-type domain. Members of the immunophilin protein family play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It has a very high substrate specificity for the four-residue peptide Ala-Ala-Pro-Phe only when the proline peptide bond is in the trans state. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels; and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse; deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.

Manufacturer: Elabscience

The Lactate Dehydrogenase (LDH) Cytotoxicity Colorimetric Assay Kit (Catalog No. E-BC-K771-M) from Elabscience is designed to assess cell membrane integrity by measuring the release of LDH, an enzyme present in the cytoplasm. Elevated LDH levels in the culture medium indicate cell damage or death, making this assay valuable for evaluating cytotoxicity in various research applications.

Manufacturer: Elabscience

The Glutathione Peroxidase 4 (GPX4) Activity Assay Kit (Catalog No. E-BC-K883-M) from Elabscience is designed to measure the activity of GPX4, an enzyme crucial for cellular defense against oxidative stress. GPX4 catalyzes the reduction of lipid hydroperoxides to their corresponding alcohols, thereby protecting cells from lipid peroxidation.

Manufacturer: Elabscience

The Pyruvate Dehydrogenase (PDH) Activity Assay Kit (Catalog No. E-BC-K650-M) from Elabscience is designed to measure PDH activity in various biological samples, including serum, plasma, urine, animal tissues, and cell cultures. PDH plays a pivotal role in cellular energy metabolism by converting pyruvate into acetyl-CoA, linking glycolysis to the tricarboxylic acid (TCA) cycle.

Manufacturer: Elabscience

The α-Ketoglutarate Dehydrogenase (α-KGDH) Activity Assay Kit (Catalog No. E-BC-K083-M) from Elabscience is designed to measure the activity of α-KGDH, a crucial enzyme in the tricarboxylic acid (TCA) cycle. This enzyme catalyzes the conversion of α-ketoglutarate to succinyl-CoA, a key step in cellular energy production.

Manufacturer: Elabscience

The Citrate Synthase (CS) Activity Assay Kit (Catalog No. E-BC-K178-M) from Elabscience is designed to measure the activity of citrate synthase, a key enzyme in the tricarboxylic acid (TCA) cycle. CS catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate, a fundamental step in cellular energy metabolism.

Manufacturer: Elabscience

The Mitochondrial Complex V (F₀F₁-ATPase/ATP Synthase) Activity Assay Kit (Catalog No. E-BC-K153-M) from Elabscience is designed to measure the activity of mitochondrial Complex V, also known as F₀F₁-ATPase or ATP synthase. This enzyme plays a crucial role in cellular energy production by synthesizing ATP from ADP and inorganic phosphate during oxidative phosphorylation.